AS 602801

CAS No. 848344-36-5

AS 602801 ( AS602801; PGL-5001; PGL 5001; Bentamapimod )

Catalog No. M17611 CAS No. 848344-36-5

AS 602801(Bentamapimod) is a novel, orally active inhibitor of JNK.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 34 In Stock
5MG 55 In Stock
10MG 91 In Stock
25MG 149 In Stock
50MG 186 In Stock
100MG 332 In Stock
500MG 1089 In Stock
1G 1971 In Stock

Biological Information

  • Product Name
    AS 602801
  • Note
    Research use only, not for human use.
  • Brief Description
    AS 602801(Bentamapimod) is a novel, orally active inhibitor of JNK.
  • Description
    Bentamapimod, also known as AS602801 and PGL5001, is a JNK Inhibitor. AS602801 induces regression of endometriotic lesions in animal models. AS602801 interrupts immune pathways. Bentamapimod induced regression of endometriotic lesions in endometriosis rodent animal models without suppressing ER action. Endometriosis is an estrogen (ER)-dependent gynecological disease caused by the growth of endometrial tissue at extrauterine sites.
  • Synonyms
    AS602801; PGL-5001; PGL 5001; Bentamapimod
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    JNK1; JNK2; JNK3
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    848344-36-5
  • Formula Weight
    457.55
  • Molecular Formula
    C25H23N5O2S
  • Purity
    98%
  • Solubility
    DMSO : 14.29 mg/mL. 31.23 mM;
  • SMILES
    N#CC(c1nc2ccccc2s1)c1nc(OCc2ccc(CN3CCOCC3)cc2)ncc1
  • Chemical Name
    2-(1,3-benzothiazol-2-yl)-2-[2-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)pyrimidin-4-yl]acetonitrile

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ferrandi C, et al. Mult Scler. 2011 Jan;17(1):43-56.
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